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تداخل‌های دارویی

Measles mumps and rubella vaccine + Sirolimus

شدت: منع مصرف

Measles mumps and rubella vaccine and Sirolimus: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Sirolimus is a potent immunosuppressant used in transplantation. It may reduce vaccine response and allow the live vaccine viruses to replicate, raising the risk of vaccine-strain infection.

معنای این تداخل به زبان ساده

Measles mumps and rubella vaccine and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Measles mumps and rubella vaccine belongs to Miscellaneous; Sirolimus belongs to Miscellaneous.

سطح شواهد: Moderate

چرا رخ می‌دهد

mTOR inhibition suppresses T-cell proliferation, impairing control of live attenuated virus.

اقدام لازم

Avoid live vaccines during sirolimus therapy. Give MMR before transplant or immunosuppression where possible.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Measles mumps and rubella vaccine و Sirolimus، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Measles mumps and rubella vaccine with Sirolimus?

MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Sirolimus is a potent immunosuppressant used in transplantation. It may reduce vaccine response and allow the live vaccine viruses to replicate, raising the risk of vaccine-strain infection.

How serious is the interaction between Measles mumps and rubella vaccine and Sirolimus?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during sirolimus therapy. Give MMR before transplant or immunosuppression where possible.

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.

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