تداخل‌های دارویی
Methoxyflurane + Tetracycline
شدت: منع مصرف
Methoxyflurane and Tetracycline: contraindicated interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Methoxyflurane releases fluoride that can injure the kidney, and tetracyclines can worsen renal function through their anti-anabolic effect. Combined use has been associated with fatal renal toxicity. Labeling advises against the combination.
معنای این تداخل به زبان ساده
Methoxyflurane and Tetracycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
Additive nephrotoxicity from methoxyflurane fluoride metabolites and tetracycline-related renal impairment.
اقدام لازم
Avoid concurrent use and choose a non-tetracycline antibiotic if methoxyflurane is needed. Monitor renal function if exposure has occurred.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Methoxyflurane و Tetracycline، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Tetracycline
پرسش‌های متداول
Can I take Methoxyflurane with Tetracycline?
MediHelp rates the interaction as contraindicated. Methoxyflurane and Tetracycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methoxyflurane releases fluoride that can injure the kidney, and tetracyclines can worsen renal function through their anti-anabolic effect. Combined use has been associated with fatal renal toxicity. Labeling advises against the combination.
How serious is the interaction between Methoxyflurane and Tetracycline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose a non-tetracycline antibiotic if methoxyflurane is needed. Monitor renal function if exposure has occurred.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Isotretinoin, Palovarotene. The full list is on the Tetracycline page.
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