تداخل‌های دارویی
Methylene blue + Venlafaxine
شدت: منع مصرف
Methylene blue and Venlafaxine: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Methylene blue is a potent MAO-A inhibitor and, combined with serotonin reuptake inhibitors like venlafaxine, can cause severe serotonin syndrome. Reactions have occurred with intravenous methylene blue given for methemoglobinemia or during surgery.
معنای این تداخل به زبان ساده
Methylene blue and Venlafaxine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
MAO-A inhibition by methylene blue added to serotonin reuptake inhibition.
اقدام لازم
Avoid unless methylene blue is needed for an emergency; then stop venlafaxine and monitor for serotonin toxicity for up to 2 weeks or until 24 hours after the last methylene blue dose, whichever comes first.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Methylene blue و Venlafaxine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Venlafaxine
- Isocarboxazid + Venlafaxine منع مصرف
- Phenelzine + Venlafaxine منع مصرف
- Procarbazine + Venlafaxine منع مصرف
- Rasagiline + Venlafaxine منع مصرف
- Safinamide + Venlafaxine منع مصرف
- Selegiline transdermal + Venlafaxine منع مصرف
پرسش‌های متداول
Can I take Methylene blue with Venlafaxine?
MediHelp rates the interaction as contraindicated. Methylene blue and Venlafaxine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylene blue is a potent MAO-A inhibitor and, combined with serotonin reuptake inhibitors like venlafaxine, can cause severe serotonin syndrome. Reactions have occurred with intravenous methylene blue given for methemoglobinemia or during surgery.
How serious is the interaction between Methylene blue and Venlafaxine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless methylene blue is needed for an emergency; then stop venlafaxine and monitor for serotonin toxicity for up to 2 weeks or until 24 hours after the last methylene blue dose, whichever comes first.
What other medicines interact with Venlafaxine?
MediHelp also lists interactions of Venlafaxine with, for example, Isocarboxazid, Phenelzine, Procarbazine. The full list is on the Venlafaxine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
