تداخل‌های دارویی
Methylprednisolone + Mifepristone
شدت: منع مصرف
Methylprednisolone and Mifepristone: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Mifepristone is a glucocorticoid receptor antagonist and can blunt the effect of corticosteroids. In patients on long-term corticosteroids it may cause adrenal insufficiency or loss of disease control, and labeling lists chronic corticosteroid therapy as a contraindication.
معنای این تداخل به زبان ساده
Methylprednisolone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Methylprednisolone belongs to Endocrine; Mifepristone belongs to Endocrine.
چرا رخ می‌دهد
Mifepristone blocks glucocorticoid receptors, opposing the effect of methylprednisolone.
اقدام لازم
Do not use mifepristone in patients on long-term corticosteroid therapy. Seek specialist advice if both are required, as usual steroid doses may be ineffective.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Methylprednisolone و Mifepristone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Methylprednisolone
- Bcg vaccine live + Methylprednisolone منع مصرف
- Measles mumps and rubella vaccine live + Methylprednisolone منع مصرف
- Measles mumps rubella and varicella vaccine live + Methylprednisolone منع مصرف
- Measles vaccine + Methylprednisolone منع مصرف
- Methylprednisolone + Rubella vaccine منع مصرف
- Methylprednisolone + Smallpox vaccine live منع مصرف
تداخلات دیگر Mifepristone
- Apixaban + Mifepristone منع مصرف
- Argatroban + Mifepristone منع مصرف
- Cisapride + Mifepristone منع مصرف
- Cortisone + Mifepristone منع مصرف
- Cyclosporin + Mifepristone منع مصرف
- Dabigatran etexilate + Mifepristone منع مصرف
پرسش‌های متداول
Can I take Methylprednisolone with Mifepristone?
MediHelp rates the interaction as contraindicated. Methylprednisolone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is a glucocorticoid receptor antagonist and can blunt the effect of corticosteroids. In patients on long-term corticosteroids it may cause adrenal insufficiency or loss of disease control, and labeling lists chronic corticosteroid therapy as a contraindication.
How serious is the interaction between Methylprednisolone and Mifepristone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use mifepristone in patients on long-term corticosteroid therapy. Seek specialist advice if both are required, as usual steroid doses may be ineffective.
What other medicines interact with Methylprednisolone?
MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Methylprednisolone page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
