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تداخل‌های دارویی

Methylprednisolone + Smallpox vaccine live

شدت: منع مصرف

Methylprednisolone and Smallpox vaccine live: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Live vaccinia vaccine can cause progressive vaccinia and generalized infection in immunosuppressed patients, including those on corticosteroids. The vaccine response may also be reduced.

معنای این تداخل به زبان ساده

Methylprednisolone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: High

چرا رخ می‌دهد

Corticosteroid-induced immunosuppression allows uncontrolled replication of live vaccinia virus.

اقدام لازم

Avoid live smallpox vaccine in patients on immunosuppressive steroids outside an emergency. If exposure risk is high, use a non-replicating vaccine where available and obtain specialist advice.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Methylprednisolone و Smallpox vaccine live، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Methylprednisolone with Smallpox vaccine live?

MediHelp rates the interaction as contraindicated. Methylprednisolone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine can cause progressive vaccinia and generalized infection in immunosuppressed patients, including those on corticosteroids. The vaccine response may also be reduced.

How serious is the interaction between Methylprednisolone and Smallpox vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live smallpox vaccine in patients on immunosuppressive steroids outside an emergency. If exposure risk is high, use a non-replicating vaccine where available and obtain specialist advice.

What other medicines interact with Methylprednisolone?

MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Methylprednisolone page.

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