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Micafungin + Saccharomyces boulardii

شدت: متوسط

Micafungin and Saccharomyces boulardii: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Micafungin has activity against yeasts and may reduce the viability of S. boulardii, lessening the probiotic effect. Live yeast probiotics have also caused fungemia in critically ill or catheterized patients.

معنای این تداخل به زبان ساده

Micafungin and Saccharomyces boulardii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

سطح شواهد: Low

چرا رخ می‌دهد

Pharmacodynamic antagonism: antifungal activity against the live yeast probiotic.

اقدام لازم

Avoid the probiotic during systemic antifungal therapy, particularly in critically ill patients or those with central lines. Resume only after antifungal treatment is completed if still needed.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Micafungin و Saccharomyces boulardii، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Micafungin with Saccharomyces boulardii?

MediHelp rates the interaction as moderate. Micafungin and Saccharomyces boulardii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Micafungin has activity against yeasts and may reduce the viability of S. boulardii, lessening the probiotic effect. Live yeast probiotics have also caused fungemia in critically ill or catheterized patients.

How serious is the interaction between Micafungin and Saccharomyces boulardii?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the probiotic during systemic antifungal therapy, particularly in critically ill patients or those with central lines. Resume only after antifungal treatment is completed if still needed.

What other medicines interact with Micafungin?

MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Sirolimus, Avapritinib. The full list is on the Micafungin page.

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