رفتن به محتوا

تداخل‌های دارویی

Oxymorphone + Sodium oxybate

شدت: منع مصرف

Oxymorphone and Sodium oxybate: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Both drugs depress the central nervous system, and combining them can cause profound sedation, respiratory depression, coma and death. Sodium oxybate labeling restricts its use with other CNS depressants such as opioids.

معنای این تداخل به زبان ساده

Oxymorphone and Sodium oxybate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Oxymorphone belongs to Musculoskeletal; Sodium oxybate belongs to Central Nervous System.

سطح شواهد: High

چرا رخ می‌دهد

Additive pharmacodynamic CNS and respiratory depression via opioid receptor and GABA-B/GHB receptor activity.

اقدام لازم

Avoid the combination; choose a non-opioid analgesic or alternative oxybate-free therapy where possible. If it cannot be avoided, use the lowest doses for the shortest time and monitor respiratory status and sedation closely.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Oxymorphone و Sodium oxybate، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Oxymorphone with Sodium oxybate?

MediHelp rates the interaction as contraindicated. Oxymorphone and Sodium oxybate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs depress the central nervous system, and combining them can cause profound sedation, respiratory depression, coma and death. Sodium oxybate labeling restricts its use with other CNS depressants such as opioids.

How serious is the interaction between Oxymorphone and Sodium oxybate?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; choose a non-opioid analgesic or alternative oxybate-free therapy where possible. If it cannot be avoided, use the lowest doses for the shortest time and monitor respiratory status and sedation closely.

What other medicines interact with Oxymorphone?

MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.

تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp

مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.

مرور از A تا Z · تداخل‌های دارویی

دریافت برنامه ورود