تداخل‌های دارویی
Oxymorphone + Phenelzine
شدت: منع مصرف
Oxymorphone and Phenelzine: contraindicated interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Opioids given with MAO inhibitors have been associated with serious reactions, including hypotension, CNS depression and in some cases serotonin-like toxicity with hyperthermia. Labeling advises against use during or within 14 days of MAOI therapy.
معنای این تداخل به زبان ساده
Oxymorphone and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Oxymorphone belongs to Musculoskeletal; Phenelzine belongs to Central Nervous System.
چرا رخ می‌دهد
MAO inhibition potentiates opioid CNS effects and may cause serotonergic or autonomic toxicity; the exact mechanism varies by opioid.
اقدام لازم
Do not use oxymorphone during or within 14 days after stopping phenelzine. Choose an alternative analgesic.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Oxymorphone و Phenelzine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Oxymorphone
- Alvimopan + Oxymorphone منع مصرف
- Ethanol + Oxymorphone منع مصرف
- Isocarboxazid + Oxymorphone منع مصرف
- Olanzapine / samidorphan + Oxymorphone منع مصرف
- Oxymorphone + Selegiline transdermal منع مصرف
- Oxymorphone + Sodium oxybate منع مصرف
تداخلات دیگر Phenelzine
- 5-HTP + Phenelzine منع مصرف
- Amitriptyline + Phenelzine منع مصرف
- Amoxapine + Phenelzine منع مصرف
- Atomoxetine + Phenelzine منع مصرف
- Benzphetamine + Phenelzine منع مصرف
- Brimonidine + Phenelzine منع مصرف
پرسش‌های متداول
Can I take Oxymorphone with Phenelzine?
MediHelp rates the interaction as contraindicated. Oxymorphone and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Opioids given with MAO inhibitors have been associated with serious reactions, including hypotension, CNS depression and in some cases serotonin-like toxicity with hyperthermia. Labeling advises against use during or within 14 days of MAOI therapy.
How serious is the interaction between Oxymorphone and Phenelzine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use oxymorphone during or within 14 days after stopping phenelzine. Choose an alternative analgesic.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.
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