Référentiel des médicaments
Erenumab
Erenumab is a medicine in the class central nervous system. It is used for migraine.
- Classe médicamenteuse: Central Nervous System
- Indications: migraine
Dernière mise à jour
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Le contenu clinique de cette page n'est disponible qu'en anglais.
L'essentiel
- Classe médicamenteuse
- Central Nervous System
- Code ATC
- N02CD01
- Formes courantes
- injection
- Dosages courants
- 70 mg/ml, 140 mg/ml
- Noms commerciaux
- 5
- Pays et marchés
- 5
Indications
Mécanisme d'action
Human monoclonal antibody; binds to the calcitonin gene-related peptide (CGRP) receptor, which is thought to be causally involved in migraine pathophysiology
Posologie adulte habituelle (résumé de la notice)
70 mg SC once monthly
Grossesse et allaitement
- Grossesse
- Unknown Limited human data; no harm to offspring in monkeys. As an IgG antibody it crosses the placenta, mainly late in pregnancy. A pregnancy registry exists. EU label: as a precaution, preferable to avoid in pregnancy.
- Allaitement
- Unknown No milk data. EU label: a risk cannot be excluded in the first days after birth; afterwards use only if clinically needed. LactMed: likely low in milk; two infants had no effects. Use with caution with a newborn.
Effets indésirables signalés
- Injection site pain.
- Constipation.
- Cramps, muscle spasms
- Immune system disorders: Rash, angioedema, anaphylaxis
Précautions particulières
- Development of hypertension and worsening of pre-existing hypertension reported
- Constipation with serious complications reported in the postmarketing setting; cases that required hospitalization, including cases where surgery was necessary reported
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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Questions fréquentes
What is Erenumab used for?
Erenumab is a medicine in the class central nervous system. It is used for Migraine.
What side effects have been reported with Erenumab?
Injection site pain., Constipation., Cramps, muscle spasms, Immune system disorders: Rash, angioedema, anaphylaxis.
Can Erenumab be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data; no harm to offspring in monkeys. As an IgG antibody it crosses the placenta, mainly late in pregnancy. A pregnancy registry exists. EU label: as a precaution, preferable to avoid in pregnancy. Breastfeeding: Unknown. No milk data. EU label: a risk cannot be excluded in the first days after birth; afterwards use only if clinically needed. LactMed: likely low in milk; two infants had no effects. Use with caution with a newborn.
What does Erenumab interact with?
MediHelp does not list a checked interaction for Erenumab yet. Always tell your pharmacist about every medicine you take.
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