Interactions médicamenteuses
Aceclofenac + Balsalazide
Gravité: Modérée
Aceclofenac and Balsalazide: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Balsalazide releases mesalamine in the colon, and aceclofenac is an NSAID. Both can affect the kidney, so combined use may add to the risk of renal impairment, particularly in dehydrated patients or those with existing kidney disease. Mesalamine itself rarely causes nephrotoxicity, but it is recognized.
Ce que signifie cette interaction, en termes simples
Aceclofenac and Balsalazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aceclofenac belongs to Musculoskeletal; Balsalazide belongs to Gastrointestinal Tract.
Pourquoi elle survient
Additive nephrotoxic potential through NSAID-mediated reduction of renal prostaglandins together with rare mesalamine-associated interstitial nephritis.
Conduite à tenir
Monitor serum creatinine and urine output periodically, especially at the start of therapy and in patients with renal risk factors. Prefer to avoid regular NSAID use in inflammatory bowel disease where possible.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Aceclofenac et Balsalazide, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.
Autres interactions de Balsalazide
Autres interactions de Aceclofenac
- Aceclofenac + Ketorolac Contre-indiquée
- Aceclofenac + Amiloride Majeure
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan Majeure
- Aceclofenac + Azilsartan-chlorthalidone Majeure
- Aceclofenac + Captopril-hydrochlorothiazide Majeure
- Aceclofenac + Celecoxib Majeure
Questions fréquentes
Can I take Aceclofenac with Balsalazide?
MediHelp rates the interaction as moderate. Aceclofenac and Balsalazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Balsalazide releases mesalamine in the colon, and aceclofenac is an NSAID. Both can affect the kidney, so combined use may add to the risk of renal impairment, particularly in dehydrated patients or those with existing kidney disease. Mesalamine itself rarely causes nephrotoxicity, but it is recognized.
How serious is the interaction between Aceclofenac and Balsalazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output periodically, especially at the start of therapy and in patients with renal risk factors. Prefer to avoid regular NSAID use in inflammatory bowel disease where possible.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Celecoxib. The full list is on the Balsalazide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
