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Interactions médicamenteuses

Acemetacin + Ginko biloba

Gravité: Modérée

Acemetacin and Ginko biloba: moderate interaction.

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Résumé

Ginkgo biloba may inhibit platelet-activating factor and platelet function, and acemetacin, an NSAID, also impairs platelet aggregation and irritates the gastric mucosa. Combined use may raise bleeding risk, including GI bleeding.

Ce que signifie cette interaction, en termes simples

Acemetacin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Low

Pourquoi elle survient

Additive antiplatelet effects from ginkgolide-mediated PAF antagonism and NSAID COX inhibition.

Conduite à tenir

Avoid routine concurrent use where possible and monitor for bruising and GI bleeding; consider gastroprotection if both are continued.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Acemetacin with Ginko biloba?

MediHelp rates the interaction as moderate. Acemetacin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo biloba may inhibit platelet-activating factor and platelet function, and acemetacin, an NSAID, also impairs platelet aggregation and irritates the gastric mucosa. Combined use may raise bleeding risk, including GI bleeding.

How serious is the interaction between Acemetacin and Ginko biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine concurrent use where possible and monitor for bruising and GI bleeding; consider gastroprotection if both are continued.

What other medicines interact with Ginko biloba?

MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.

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