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MediHelp Référence médicamenteuse

Interactions médicamenteuses

Ginko biloba + Ketorolac

Gravité: Majeure

Ginko biloba and Ketorolac: major interaction.

Dernière mise à jour

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Résumé

Ketorolac is a potent NSAID with marked antiplatelet effect and a labeled bleeding warning, and ginkgo biloba adds further antiplatelet activity. Together they may substantially raise the risk of serious bleeding, including gastrointestinal and perioperative hemorrhage.

Ce que signifie cette interaction, en termes simples

Ginko biloba and Ketorolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ginko biloba belongs to Gastrointestinal Tract; Ketorolac belongs to Musculoskeletal.

Niveau de preuve: Low

Pourquoi elle survient

Additive antiplatelet effects: ginkgolides antagonize platelet-activating factor while ketorolac strongly inhibits COX-1-mediated thromboxane production.

Conduite à tenir

Avoid ginkgo during ketorolac therapy and stop it before surgery or procedures with bleeding risk. Monitor for bleeding if the combination has been taken.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Ginko biloba with Ketorolac?

MediHelp rates the interaction as major. Ginko biloba and Ketorolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ketorolac is a potent NSAID with marked antiplatelet effect and a labeled bleeding warning, and ginkgo biloba adds further antiplatelet activity. Together they may substantially raise the risk of serious bleeding, including gastrointestinal and perioperative hemorrhage.

How serious is the interaction between Ginko biloba and Ketorolac?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ginkgo during ketorolac therapy and stop it before surgery or procedures with bleeding risk. Monitor for bleeding if the combination has been taken.

What other medicines interact with Ginko biloba?

MediHelp also lists interactions of Ginko biloba with, for example, Abciximab, Aceclofenac, Acemetacin. The full list is on the Ginko biloba page.

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