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Interactions médicamenteuses

Alteplase + Ginko biloba

Gravité: Modérée

Alteplase and Ginko biloba: moderate interaction.

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Résumé

Ginkgo biloba may impair platelet function, and alteplase carries a substantial bleeding risk. Combining them could theoretically increase hemorrhage, including intracranial bleeding, though clinical evidence is limited.

Ce que signifie cette interaction, en termes simples

Alteplase and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Alteplase belongs to Cardiovascular; Ginko biloba belongs to Gastrointestinal Tract.

Niveau de preuve: Low

Pourquoi elle survient

Ginkgolides inhibit platelet-activating factor, adding antiplatelet effects to the thrombolytic action of alteplase.

Conduite à tenir

Ask about herbal use before thrombolysis and stop ginkgo in elective settings. Monitor closely for bleeding after alteplase if exposure has occurred.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Alteplase with Ginko biloba?

MediHelp rates the interaction as moderate. Alteplase and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo biloba may impair platelet function, and alteplase carries a substantial bleeding risk. Combining them could theoretically increase hemorrhage, including intracranial bleeding, though clinical evidence is limited.

How serious is the interaction between Alteplase and Ginko biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use before thrombolysis and stop ginkgo in elective settings. Monitor closely for bleeding after alteplase if exposure has occurred.

What other medicines interact with Ginko biloba?

MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.

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