Interactions médicamenteuses
Aclidinium + Dicyclomine
Gravité: Modérée
Aclidinium and Dicyclomine: moderate interaction.
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Résumé
Both drugs are antimuscarinic. Inhaled aclidinium has low systemic exposure, but combined use may add to anticholinergic effects such as dry mouth, urinary retention, constipation and blurred vision.
Ce que signifie cette interaction, en termes simples
Aclidinium and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Additive muscarinic receptor antagonism.
Conduite à tenir
Avoid regular use of other anticholinergics with aclidinium where possible. Monitor for urinary retention, constipation and narrow-angle glaucoma symptoms.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Dicyclomine
- Clozapine + Dicyclomine Majeure
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- Dicyclomine + Imipramine Majeure
- Dicyclomine + Pramlintide Majeure
- Abobotulinumtoxina + Dicyclomine Modérée
- Amantadine + Dicyclomine Modérée
Questions fréquentes
Can I take Aclidinium with Dicyclomine?
MediHelp rates the interaction as moderate. Aclidinium and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are antimuscarinic. Inhaled aclidinium has low systemic exposure, but combined use may add to anticholinergic effects such as dry mouth, urinary retention, constipation and blurred vision.
How serious is the interaction between Aclidinium and Dicyclomine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular use of other anticholinergics with aclidinium where possible. Monitor for urinary retention, constipation and narrow-angle glaucoma symptoms.
What other medicines interact with Dicyclomine?
MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.
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