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Interactions médicamenteuses

Amantadine + Dicyclomine

Gravité: Modérée

Amantadine and Dicyclomine: moderate interaction.

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Résumé

Both drugs have anticholinergic activity, so together they can cause dry mouth, constipation, urinary retention, blurred vision, confusion and hallucinations. Older adults and those with prostatic enlargement or glaucoma are most at risk.

Ce que signifie cette interaction, en termes simples

Amantadine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amantadine belongs to Anti Virals; Dicyclomine belongs to Respiratory.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive anticholinergic pharmacodynamic effects.

Conduite à tenir

Monitor for anticholinergic toxicity and cognitive changes, and reduce the dose or choose an alternative if they occur, particularly in the elderly.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Amantadine with Dicyclomine?

MediHelp rates the interaction as moderate. Amantadine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have anticholinergic activity, so together they can cause dry mouth, constipation, urinary retention, blurred vision, confusion and hallucinations. Older adults and those with prostatic enlargement or glaucoma are most at risk.

How serious is the interaction between Amantadine and Dicyclomine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic toxicity and cognitive changes, and reduce the dose or choose an alternative if they occur, particularly in the elderly.

What other medicines interact with Dicyclomine?

MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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