Interactions médicamenteuses
Adenovirus types 4 and 7 live + Daunorubicin
Gravité: Contre-indiquée
Adenovirus types 4 and 7 live and Daunorubicin: contraindicated interaction.
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Résumé
Daunorubicin is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may fail to produce protection and could cause disseminated vaccine-strain infection. Live vaccines should not be given to patients on cytotoxic chemotherapy.
Ce que signifie cette interaction, en termes simples
Adenovirus types 4 and 7 live and Daunorubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Immunosuppression from the cytotoxic agent impairs the immune response and allows the live attenuated virus to replicate uncontrolled.
Conduite à tenir
Do not give the live vaccine during chemotherapy or for at least 3 months after it ends. Check immune recovery before vaccination.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Daunorubicin
- Belatacept + Daunorubicin Majeure
- Cyclosporine + Daunorubicin Majeure
- Cyclosporin + Daunorubicin Majeure
- Daunorubicin + Dengue vaccine Majeure
- Daunorubicin + Etrasimod Majeure
- Daunorubicin + Fingolimod Majeure
Questions fréquentes
Can I take Adenovirus types 4 and 7 live with Daunorubicin?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Daunorubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Daunorubicin is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may fail to produce protection and could cause disseminated vaccine-strain infection. Live vaccines should not be given to patients on cytotoxic chemotherapy.
How serious is the interaction between Adenovirus types 4 and 7 live and Daunorubicin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live vaccine during chemotherapy or for at least 3 months after it ends. Check immune recovery before vaccination.
What other medicines interact with Daunorubicin?
MediHelp also lists interactions of Daunorubicin with, for example, Belatacept, Cyclosporine, Cyclosporin. The full list is on the Daunorubicin page.
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