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Interactions médicamenteuses

Daunorubicin + Dengue vaccine

Gravité: Majeure

Daunorubicin and Dengue vaccine: major interaction.

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Résumé

Dengue vaccine (Dengvaxia) is a live attenuated vaccine. In patients receiving myelosuppressive chemotherapy, immune response may be reduced and the vaccine virus could cause disease.

Ce que signifie cette interaction, en termes simples

Daunorubicin and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Niveau de preuve: Moderate

Pourquoi elle survient

Chemotherapy-induced immunosuppression impairs vaccine response and permits live vaccine virus replication.

Conduite à tenir

Avoid live vaccines during chemotherapy and until immune recovery, as advised by the vaccine labeling and oncology guidance.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Daunorubicin with Dengue vaccine?

MediHelp rates the interaction as major. Daunorubicin and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine (Dengvaxia) is a live attenuated vaccine. In patients receiving myelosuppressive chemotherapy, immune response may be reduced and the vaccine virus could cause disease.

How serious is the interaction between Daunorubicin and Dengue vaccine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and until immune recovery, as advised by the vaccine labeling and oncology guidance.

What other medicines interact with Daunorubicin?

MediHelp also lists interactions of Daunorubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclosporine. The full list is on the Daunorubicin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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