Interactions médicamenteuses
Alogliptin-metformin + Patiromer
Gravité: Modérée
Alogliptin-metformin and Patiromer: moderate interaction.
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Résumé
Patiromer is a non-absorbed polymer that may bind co-administered oral drugs in the gut and lower their absorption. Metformin exposure could be reduced, weakening glucose control.
Ce que signifie cette interaction, en termes simples
Alogliptin-metformin and Patiromer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-metformin belongs to Endocrine; Patiromer belongs to Miscellaneous.
Pourquoi elle survient
Binding of the oral drug to the polymer in the gastrointestinal tract reduces its absorption.
Conduite à tenir
Give patiromer at least 3 hours before or after the alogliptin-metformin dose. Monitor blood glucose if timing cannot be separated.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Alogliptin-metformin
Autres interactions de Patiromer
- Canagliflozin-metformin + Patiromer Modérée
- Carvedilol + Patiromer Modérée
- Ciprofloxacin + Patiromer Modérée
- Dapagliflozin-metformin + Patiromer Modérée
- Empagliflozin-metformin + Patiromer Modérée
- Glipizide-metformin + Patiromer Modérée
Questions fréquentes
Can I take Alogliptin-metformin with Patiromer?
MediHelp rates the interaction as moderate. Alogliptin-metformin and Patiromer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patiromer is a non-absorbed polymer that may bind co-administered oral drugs in the gut and lower their absorption. Metformin exposure could be reduced, weakening glucose control.
How serious is the interaction between Alogliptin-metformin and Patiromer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give patiromer at least 3 hours before or after the alogliptin-metformin dose. Monitor blood glucose if timing cannot be separated.
What other medicines interact with Alogliptin-metformin?
MediHelp also lists interactions of Alogliptin-metformin with, for example, Clozapine, Contrast media, Diatrizoate. The full list is on the Alogliptin-metformin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.