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Interactions médicamenteuses

Aminolevulinic acid + Tetracycline

Gravité: Modérée

Aminolevulinic acid and Tetracycline: moderate interaction.

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Résumé

Oral aminolevulinic acid causes protoporphyrin accumulation and photosensitivity, and tetracyclines are also phototoxic. Using them together may increase the risk of severe phototoxic skin reactions.

Ce que signifie cette interaction, en termes simples

Aminolevulinic acid and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Aminolevulinic acid belongs to Miscellaneous; Tetracycline belongs to Anti Bacterial.

Niveau de preuve: Low

Pourquoi elle survient

Additive phototoxicity from photosensitizing agents.

Conduite à tenir

Avoid giving tetracycline during the 24 hours around aminolevulinic acid administration and counsel the patient on strict sun and bright light protection.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Aminolevulinic acid with Tetracycline?

MediHelp rates the interaction as moderate. Aminolevulinic acid and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral aminolevulinic acid causes protoporphyrin accumulation and photosensitivity, and tetracyclines are also phototoxic. Using them together may increase the risk of severe phototoxic skin reactions.

How serious is the interaction between Aminolevulinic acid and Tetracycline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving tetracycline during the 24 hours around aminolevulinic acid administration and counsel the patient on strict sun and bright light protection.

What other medicines interact with Tetracycline?

MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.

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