Interactions médicamenteuses
Methoxyflurane + Tetracycline
Gravité: Contre-indiquée
Methoxyflurane and Tetracycline: contraindicated interaction.
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Résumé
Methoxyflurane releases fluoride that can injure the kidney, and tetracyclines can worsen renal function through their anti-anabolic effect. Combined use has been associated with fatal renal toxicity. Labeling advises against the combination.
Ce que signifie cette interaction, en termes simples
Methoxyflurane and Tetracycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Additive nephrotoxicity from methoxyflurane fluoride metabolites and tetracycline-related renal impairment.
Conduite à tenir
Avoid concurrent use and choose a non-tetracycline antibiotic if methoxyflurane is needed. Monitor renal function if exposure has occurred.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Tetracycline
- Acitretin + Tetracycline Contre-indiquée
- Isotretinoin + Tetracycline Majeure
- Palovarotene + Tetracycline Majeure
- Strontium ranelate + Tetracycline Majeure
- Tetracycline + Tretinoin Majeure
- Tetracycline + Typhoid vaccine live Majeure
Questions fréquentes
Can I take Methoxyflurane with Tetracycline?
MediHelp rates the interaction as contraindicated. Methoxyflurane and Tetracycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methoxyflurane releases fluoride that can injure the kidney, and tetracyclines can worsen renal function through their anti-anabolic effect. Combined use has been associated with fatal renal toxicity. Labeling advises against the combination.
How serious is the interaction between Methoxyflurane and Tetracycline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose a non-tetracycline antibiotic if methoxyflurane is needed. Monitor renal function if exposure has occurred.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Isotretinoin, Palovarotene. The full list is on the Tetracycline page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
