Aller au contenu
MediHelp
MediHelp Référence médicamenteuse

Interactions médicamenteuses

Amiodarone + Atenolol

Gravité: Majeure

Amiodarone and Atenolol: major interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Both drugs slow sinus rate and AV nodal conduction, so combined use can cause significant bradycardia, AV block or sinus arrest. The risk is highest in older patients and those with existing conduction disease.

Ce que signifie cette interaction, en termes simples

Amiodarone and Atenolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Amiodarone belongs to Cardiovascular; Atenolol belongs to Cardiovascular.

Niveau de preuve: High

Pourquoi elle survient

Additive negative chronotropic and dromotropic effects through beta-blockade and amiodarone's multichannel and beta-blocking actions.

Conduite à tenir

Obtain a baseline ECG and monitor heart rate and PR interval, reducing the atenolol dose or stopping one agent if symptomatic bradycardia or block develops.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Amiodarone et Atenolol, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
Créer un compte gratuit Se connecter

Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.

Questions fréquentes

Can I take Amiodarone with Atenolol?

MediHelp rates the interaction as major. Amiodarone and Atenolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs slow sinus rate and AV nodal conduction, so combined use can cause significant bradycardia, AV block or sinus arrest. The risk is highest in older patients and those with existing conduction disease.

How serious is the interaction between Amiodarone and Atenolol?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor heart rate and PR interval, reducing the atenolol dose or stopping one agent if symptomatic bradycardia or block develops.

What other medicines interact with Atenolol?

MediHelp also lists interactions of Atenolol with, for example, Amifostine, Atenolol-chlorthalidone, Betaxolol. The full list is on the Atenolol page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Télécharger surApp Store Disponible surGoogle Play

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter