Interactions médicamenteuses
Amlodipine-olmesartan-hydrochlorothiazide + Carbidopa
Gravité: Modérée
Amlodipine-olmesartan-hydrochlorothiazide and Carbidopa: moderate interaction.
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Résumé
Carbidopa given with levodopa can cause orthostatic hypotension, which may be additive with antihypertensives. The effect is mainly seen when levodopa therapy is started or increased.
Ce que signifie cette interaction, en termes simples
Amlodipine-olmesartan-hydrochlorothiazide and Carbidopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Carbidopa belongs to Central Nervous System.
Pourquoi elle survient
Additive hypotensive effects from levodopa-derived dopamine and antihypertensive vasodilation and diuresis.
Conduite à tenir
Monitor sitting and standing blood pressure when starting or titrating levodopa/carbidopa and reduce antihypertensive doses if symptomatic hypotension occurs.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contre-indiquée
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contre-indiquée
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contre-indiquée
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Majeure
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Majeure
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Majeure
Autres interactions de Carbidopa
Questions fréquentes
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Carbidopa?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Carbidopa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbidopa given with levodopa can cause orthostatic hypotension, which may be additive with antihypertensives. The effect is mainly seen when levodopa therapy is started or increased.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Carbidopa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sitting and standing blood pressure when starting or titrating levodopa/carbidopa and reduce antihypertensive doses if symptomatic hypotension occurs.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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