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Interactions médicamenteuses

Amoxicillin + Mycophenolate

Gravité: Modérée

Amoxicillin and Mycophenolate: moderate interaction.

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Résumé

Amoxicillin may lower mycophenolic acid exposure, particularly the late concentration peak, which can reduce immunosuppression. The effect is usually modest.

Ce que signifie cette interaction, en termes simples

Amoxicillin and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Moderate

Pourquoi elle survient

Gut flora alteration reduces deconjugation of mycophenolic acid glucuronide, impairing enterohepatic recirculation.

Conduite à tenir

Monitor for graft rejection and consider mycophenolic acid level monitoring in high-risk patients during antibiotic therapy.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Amoxicillin with Mycophenolate?

MediHelp rates the interaction as moderate. Amoxicillin and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amoxicillin may lower mycophenolic acid exposure, particularly the late concentration peak, which can reduce immunosuppression. The effect is usually modest.

How serious is the interaction between Amoxicillin and Mycophenolate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for graft rejection and consider mycophenolic acid level monitoring in high-risk patients during antibiotic therapy.

What other medicines interact with Amoxicillin?

MediHelp also lists interactions of Amoxicillin with, for example, Methotrexate, Bcg vaccine live, Cholera vaccine. The full list is on the Amoxicillin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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