Interactions médicamenteuses
Amoxicillin-clavulanic acid + Bcg vaccine live
Gravité: Modérée
Amoxicillin-clavulanic acid and Bcg vaccine live: moderate interaction.
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Résumé
Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Amoxicillin has limited activity against BCG, but labeling for live bacterial vaccines advises avoiding concurrent antibiotics.
Ce que signifie cette interaction, en termes simples
Amoxicillin-clavulanic acid and Bcg vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Antibacterial activity may reduce replication of the live vaccine organism, lessening the immune response.
Conduite à tenir
Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Amoxicillin-clavulanic acid
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Questions fréquentes
Can I take Amoxicillin-clavulanic acid with Bcg vaccine live?
MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Bcg vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG contains viable bacteria, and antibiotics active against them can reduce vaccine take. Amoxicillin has limited activity against BCG, but labeling for live bacterial vaccines advises avoiding concurrent antibiotics.
How serious is the interaction between Amoxicillin-clavulanic acid and Bcg vaccine live?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer BCG vaccination until antibiotic therapy is complete, where the vaccine is not urgent.
What other medicines interact with Amoxicillin-clavulanic acid?
MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.
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