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Interactions médicamenteuses

Anagrelide + Cilostazol

Gravité: Majeure

Anagrelide and Cilostazol: major interaction.

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Résumé

Both drugs are PDE3 inhibitors, so combining them may amplify cardiovascular effects such as tachycardia, palpitations, fluid retention and hypotension. Anagrelide labeling advises caution with other PDE3 inhibitors, and bleeding risk may also be additive.

Ce que signifie cette interaction, en termes simples

Anagrelide and Cilostazol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Anagrelide belongs to Cardiovascular; Cilostazol belongs to Cardiovascular.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive PDE3 inhibition producing enhanced inotropic, chronotropic, vasodilatory and antiplatelet effects.

Conduite à tenir

Avoid the combination where possible; if used, monitor heart rate, blood pressure, signs of heart failure and bleeding closely.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Anagrelide with Cilostazol?

MediHelp rates the interaction as major. Anagrelide and Cilostazol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs are PDE3 inhibitors, so combining them may amplify cardiovascular effects such as tachycardia, palpitations, fluid retention and hypotension. Anagrelide labeling advises caution with other PDE3 inhibitors, and bleeding risk may also be additive.

How serious is the interaction between Anagrelide and Cilostazol?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if used, monitor heart rate, blood pressure, signs of heart failure and bleeding closely.

What other medicines interact with Cilostazol?

MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Betrixaban, Cobicistat. The full list is on the Cilostazol page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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