Interactions médicamenteuses
Certolizumab pegol + Measles mumps and rubella vaccine
Gravité: Contre-indiquée
Certolizumab pegol and Measles mumps and rubella vaccine: contraindicated interaction.
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Résumé
The live attenuated vaccine relies on a competent immune system to limit viral replication, and certolizumab pegol (a TNF-alpha antagonist) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.
Ce que signifie cette interaction, en termes simples
Certolizumab pegol and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Certolizumab pegol belongs to Musculoskeletal; Measles mumps and rubella vaccine belongs to Miscellaneous.
Pourquoi elle survient
Certolizumab pegol-mediated immunosuppression allows replication of a live attenuated virus
Conduite à tenir
Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contre-indiquée
- Anakinra + Measles mumps and rubella vaccine Contre-indiquée
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contre-indiquée
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contre-indiquée
- Azathioprine + Measles mumps and rubella vaccine Contre-indiquée
- Basiliximab + Measles mumps and rubella vaccine Contre-indiquée
Autres interactions de Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contre-indiquée
- Bcg intravesical live + Certolizumab pegol Contre-indiquée
- Bcg vaccine live + Certolizumab pegol Contre-indiquée
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Certolizumab pegol + Measles mumps and rubella vaccine live Contre-indiquée
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live Contre-indiquée
Questions fréquentes
Can I take Certolizumab pegol with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live attenuated vaccine relies on a competent immune system to limit viral replication, and certolizumab pegol (a TNF-alpha antagonist) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.
How serious is the interaction between Certolizumab pegol and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
