Interactions médicamenteuses
Anastrozole + Bazedoxifene / conjugated estrogens
Gravité: Contre-indiquée
Anastrozole and Bazedoxifene / conjugated estrogens: contraindicated interaction.
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Résumé
Anastrozole lowers estrogen levels in postmenopausal women with hormone receptor-positive breast cancer, whereas conjugated estrogens supply estrogen. The therapy opposes the intended anti-estrogen effect and may reduce cancer control.
Ce que signifie cette interaction, en termes simples
Anastrozole and Bazedoxifene / conjugated estrogens are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Pharmacodynamic antagonism: exogenous estrogen counteracts aromatase inhibition.
Conduite à tenir
Do not combine. Use non-hormonal options for vasomotor symptoms in patients on anastrozole.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Anastrozole
- Anastrozole + Bazedoxifene-conjugated estrogens Contre-indiquée
- Anastrozole + Conjugated estrogens Contre-indiquée
- Anastrozole + Estradiol Contre-indiquée
- Anastrozole + Estrogens conjugated synthetic Contre-indiquée
- Anastrozole + Estrogens esterified Contre-indiquée
- Anastrozole + Estropipate Contre-indiquée
Questions fréquentes
Can I take Anastrozole with Bazedoxifene / conjugated estrogens?
MediHelp rates the interaction as contraindicated. Anastrozole and Bazedoxifene / conjugated estrogens are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Anastrozole lowers estrogen levels in postmenopausal women with hormone receptor-positive breast cancer, whereas conjugated estrogens supply estrogen. The therapy opposes the intended anti-estrogen effect and may reduce cancer control.
How serious is the interaction between Anastrozole and Bazedoxifene / conjugated estrogens?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Use non-hormonal options for vasomotor symptoms in patients on anastrozole.
What other medicines interact with Anastrozole?
MediHelp also lists interactions of Anastrozole with, for example, Bazedoxifene-conjugated estrogens, Conjugated estrogens, Estradiol. The full list is on the Anastrozole page.
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