Interactions médicamenteuses
Anti-thymocyte + Measles mumps and rubella vaccine live
Gravité: Contre-indiquée
Anti-thymocyte and Measles mumps and rubella vaccine live: contraindicated interaction.
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Résumé
The live MMR vaccine can cause disseminated vaccine-virus infection in patients heavily immunosuppressed by anti-thymocyte globulin. Immunogenicity is also reduced.
Ce que signifie cette interaction, en termes simples
Anti-thymocyte and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Impaired cell-mediated immunity permits uncontrolled replication of live attenuated viruses.
Conduite à tenir
Avoid live MMR vaccine during and after anti-thymocyte globulin until immune recovery is documented. If needed, vaccinate at least 4 weeks before therapy.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Contre-indiquée
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Anti-thymocyte + Measles vaccine Contre-indiquée
- Anti-thymocyte + Rotavirus oral vaccine live Contre-indiquée
- Anti-thymocyte + Rubella vaccine Contre-indiquée
Questions fréquentes
Can I take Anti-thymocyte with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Anti-thymocyte and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live MMR vaccine can cause disseminated vaccine-virus infection in patients heavily immunosuppressed by anti-thymocyte globulin. Immunogenicity is also reduced.
How serious is the interaction between Anti-thymocyte and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live MMR vaccine during and after anti-thymocyte globulin until immune recovery is documented. If needed, vaccinate at least 4 weeks before therapy.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps rubella and varicella vaccine live. The full list is on the Anti-thymocyte page.
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