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Interactions médicamenteuses

Anti-thymocyte + Rotavirus oral vaccine live

Gravité: Contre-indiquée

Anti-thymocyte and Rotavirus oral vaccine live: contraindicated interaction.

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Résumé

Rotavirus vaccine is live attenuated and could cause prolonged or serious vaccine-virus infection in a patient profoundly immunosuppressed by anti-thymocyte globulin. The vaccine response is also likely poor.

Ce que signifie cette interaction, en termes simples

Anti-thymocyte and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Niveau de preuve: Moderate

Pourquoi elle survient

Impaired immunity allows replication of live attenuated virus.

Conduite à tenir

Do not give live rotavirus vaccine during anti-thymocyte globulin therapy; defer until immune recovery is confirmed.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Anti-thymocyte with Rotavirus oral vaccine live?

MediHelp rates the interaction as contraindicated. Anti-thymocyte and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rotavirus vaccine is live attenuated and could cause prolonged or serious vaccine-virus infection in a patient profoundly immunosuppressed by anti-thymocyte globulin. The vaccine response is also likely poor.

How serious is the interaction between Anti-thymocyte and Rotavirus oral vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live rotavirus vaccine during anti-thymocyte globulin therapy; defer until immune recovery is confirmed.

What other medicines interact with Anti-thymocyte?

MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.

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