Interactions médicamenteuses
Anti-thymocyte + Bcg vaccine live
Gravité: Contre-indiquée
Anti-thymocyte and Bcg vaccine live: contraindicated interaction.
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Résumé
Anti-thymocyte globulin causes profound T-cell depletion, so a live attenuated vaccine may cause disseminated infection. The vaccine is also likely to be ineffective in this setting.
Ce que signifie cette interaction, en termes simples
Anti-thymocyte and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Profound T-cell immunosuppression allows uncontrolled replication of live attenuated BCG.
Conduite à tenir
Do not give BCG during or after anti-thymocyte globulin until immune recovery is confirmed by the specialist team. Give it at least several weeks before starting immunosuppression when feasible.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Anti-thymocyte
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Anti-thymocyte + Measles mumps and rubella vaccine live Contre-indiquée
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Anti-thymocyte + Measles vaccine Contre-indiquée
- Anti-thymocyte + Rotavirus oral vaccine live Contre-indiquée
- Anti-thymocyte + Rubella vaccine Contre-indiquée
Questions fréquentes
Can I take Anti-thymocyte with Bcg vaccine live?
MediHelp rates the interaction as contraindicated. Anti-thymocyte and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Anti-thymocyte globulin causes profound T-cell depletion, so a live attenuated vaccine may cause disseminated infection. The vaccine is also likely to be ineffective in this setting.
How serious is the interaction between Anti-thymocyte and Bcg vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during or after anti-thymocyte globulin until immune recovery is confirmed by the specialist team. Give it at least several weeks before starting immunosuppression when feasible.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Anti-thymocyte page.
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