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Interactions médicamenteuses

Arformoterol + Desipramine

Gravité: Majeure

Arformoterol and Desipramine: major interaction.

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Résumé

Tricyclic antidepressants may potentiate the cardiovascular effects of long-acting beta agonists such as arformoterol, including QT prolongation, tachycardia and arrhythmia. Labeling advises extra caution with this combination.

Ce que signifie cette interaction, en termes simples

Arformoterol and Desipramine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Arformoterol belongs to Respiratory; Desipramine belongs to Central Nervous System.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive adrenergic stimulation and QT prolongation.

Conduite à tenir

Monitor ECG, heart rate and blood pressure, and consider an alternative bronchodilator in patients with cardiac risk. Correct potassium abnormalities.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Arformoterol with Desipramine?

MediHelp rates the interaction as major. Arformoterol and Desipramine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tricyclic antidepressants may potentiate the cardiovascular effects of long-acting beta agonists such as arformoterol, including QT prolongation, tachycardia and arrhythmia. Labeling advises extra caution with this combination.

How serious is the interaction between Arformoterol and Desipramine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate and blood pressure, and consider an alternative bronchodilator in patients with cardiac risk. Correct potassium abnormalities.

What other medicines interact with Desipramine?

MediHelp also lists interactions of Desipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Desipramine page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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