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MediHelp Référence médicamenteuse

Interactions médicamenteuses

Arformoterol + Fluticasone-salmeterol

Gravité: Majeure

Arformoterol and Fluticasone-salmeterol: major interaction.

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Résumé

Arformoterol and salmeterol are both long-acting beta-2 agonists, so combining them duplicates therapy. This increases the risk of tachycardia, arrhythmia, tremor and hypokalemia without added benefit.

Ce que signifie cette interaction, en termes simples

Arformoterol and Fluticasone-salmeterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Arformoterol belongs to Respiratory; Fluticasone-salmeterol belongs to Respiratory.

Niveau de preuve: Moderate

Pourquoi elle survient

Duplicate beta-2 adrenergic receptor agonism with additive cardiovascular and metabolic effects.

Conduite à tenir

Avoid using two long-acting beta-2 agonists together; stop one. Monitor heart rate and potassium if overlap occurs.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Arformoterol with Fluticasone-salmeterol?

MediHelp rates the interaction as major. Arformoterol and Fluticasone-salmeterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Arformoterol and salmeterol are both long-acting beta-2 agonists, so combining them duplicates therapy. This increases the risk of tachycardia, arrhythmia, tremor and hypokalemia without added benefit.

How serious is the interaction between Arformoterol and Fluticasone-salmeterol?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two long-acting beta-2 agonists together; stop one. Monitor heart rate and potassium if overlap occurs.

What other medicines interact with Fluticasone-salmeterol?

MediHelp also lists interactions of Fluticasone-salmeterol with, for example, Darunavir, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Fosamprenavir. The full list is on the Fluticasone-salmeterol page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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