Interactions médicamenteuses
Aztreonam + Typhoid vaccine live
Gravité: Modérée
Aztreonam and Typhoid vaccine live: moderate interaction.
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Résumé
Oral live typhoid vaccine depends on viable attenuated Salmonella Typhi in the gut. Aztreonam is active against gram-negative bacilli including Salmonella and could reduce vaccine viability and immune response.
Ce que signifie cette interaction, en termes simples
Aztreonam and Typhoid vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Antibacterial activity may inhibit the live attenuated Salmonella strain, reducing immunogenicity.
Conduite à tenir
Give live oral typhoid vaccine at least 3 days after the last aztreonam dose, or vaccinate beforehand. Use the inactivated Vi vaccine if timing cannot be separated.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Aztreonam
Questions fréquentes
Can I take Aztreonam with Typhoid vaccine live?
MediHelp rates the interaction as moderate. Aztreonam and Typhoid vaccine live can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral live typhoid vaccine depends on viable attenuated Salmonella Typhi in the gut. Aztreonam is active against gram-negative bacilli including Salmonella and could reduce vaccine viability and immune response.
How serious is the interaction between Aztreonam and Typhoid vaccine live?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give live oral typhoid vaccine at least 3 days after the last aztreonam dose, or vaccinate beforehand. Use the inactivated Vi vaccine if timing cannot be separated.
What other medicines interact with Aztreonam?
MediHelp also lists interactions of Aztreonam with, for example, Cefoxitin, Cholera vaccine, Microbiota. The full list is on the Aztreonam page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
