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Interactions médicamenteuses

Baricitinib + Bcg vaccine live

Gravité: Contre-indiquée

Baricitinib and Bcg vaccine live: contraindicated interaction.

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Résumé

Baricitinib-related immunosuppression raises the risk of disseminated BCG infection from the live vaccine and may reduce its effectiveness.

Ce que signifie cette interaction, en termes simples

Baricitinib and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Niveau de preuve: Moderate

Pourquoi elle survient

JAK inhibition-induced immunosuppression allows uncontrolled replication of live attenuated bacteria.

Conduite à tenir

Do not give BCG vaccine during baricitinib treatment. Vaccinate before starting therapy where indicated, following current guidelines.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Baricitinib with Bcg vaccine live?

MediHelp rates the interaction as contraindicated. Baricitinib and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Baricitinib-related immunosuppression raises the risk of disseminated BCG infection from the live vaccine and may reduce its effectiveness.

How serious is the interaction between Baricitinib and Bcg vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG vaccine during baricitinib treatment. Vaccinate before starting therapy where indicated, following current guidelines.

What other medicines interact with Baricitinib?

MediHelp also lists interactions of Baricitinib with, for example, Adenovirus types 4 and 7 live, Tofacitinib, Upadacitinib. The full list is on the Baricitinib page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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