Interactions médicamenteuses
Basiliximab + Ciltacabtagene autoleucel
Gravité: Majeure
Basiliximab and Ciltacabtagene autoleucel: major interaction.
Dernière mise à jour
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Résumé
Basiliximab blocks IL-2 receptor on activated T cells, which could impair expansion and activity of CAR T cells and weaken efficacy. It also adds to infection risk after lymphodepletion.
Ce que signifie cette interaction, en termes simples
Basiliximab and Ciltacabtagene autoleucel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Basiliximab belongs to Miscellaneous; Ciltacabtagene autoleucel belongs to Miscellaneous.
Pourquoi elle survient
Pharmacodynamic antagonism of CAR T-cell proliferation through IL-2 receptor blockade and additive immunosuppression.
Conduite à tenir
Avoid basiliximab around CAR T infusion unless clearly needed; coordinate with the treating oncology team and monitor for infection.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Basiliximab
- Basiliximab + Bcg vaccine live Contre-indiquée
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Basiliximab + Measles mumps and rubella vaccine Contre-indiquée
- Basiliximab + Measles mumps and rubella vaccine live Contre-indiquée
- Basiliximab + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Basiliximab + Measles vaccine Contre-indiquée
Autres interactions de Ciltacabtagene autoleucel
Questions fréquentes
Can I take Basiliximab with Ciltacabtagene autoleucel?
MediHelp rates the interaction as major. Basiliximab and Ciltacabtagene autoleucel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Basiliximab blocks IL-2 receptor on activated T cells, which could impair expansion and activity of CAR T cells and weaken efficacy. It also adds to infection risk after lymphodepletion.
How serious is the interaction between Basiliximab and Ciltacabtagene autoleucel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid basiliximab around CAR T infusion unless clearly needed; coordinate with the treating oncology team and monitor for infection.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
