Interactions médicamenteuses
Benzhydrocodone / acetaminophen + Cariprazine
Gravité: Majeure
Benzhydrocodone / acetaminophen and Cariprazine: major interaction.
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Résumé
Cariprazine combined with an opioid such as benzhydrocodone may cause additive sedation, respiratory depression, coma and death in severe cases. Impaired psychomotor performance is also expected.
Ce que signifie cette interaction, en termes simples
Benzhydrocodone / acetaminophen and Cariprazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive CNS and respiratory depression from opioid agonism and antipsychotic sedation.
Conduite à tenir
Reserve the combination for patients without adequate alternatives, limit dose and duration, and monitor for sedation and respiratory depression.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Cariprazine
- Alfentanil + Cariprazine Majeure
- Amisulpride + Cariprazine Majeure
- Amobarbital + Cariprazine Majeure
- Apalutamide + Cariprazine Majeure
- Atazanavir + Cariprazine Majeure
- Brexanolone + Cariprazine Majeure
Questions fréquentes
Can I take Benzhydrocodone / acetaminophen with Cariprazine?
MediHelp rates the interaction as major. Benzhydrocodone / acetaminophen and Cariprazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cariprazine combined with an opioid such as benzhydrocodone may cause additive sedation, respiratory depression, coma and death in severe cases. Impaired psychomotor performance is also expected.
How serious is the interaction between Benzhydrocodone / acetaminophen and Cariprazine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reserve the combination for patients without adequate alternatives, limit dose and duration, and monitor for sedation and respiratory depression.
What other medicines interact with Cariprazine?
MediHelp also lists interactions of Cariprazine with, for example, Alfentanil, Amisulpride, Amobarbital. The full list is on the Cariprazine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
