Interactions médicamenteuses
Benzphetamine + Tranylcypromine
Gravité: Contre-indiquée
Benzphetamine and Tranylcypromine: contraindicated interaction.
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Résumé
Benzphetamine is a sympathomimetic anorectic that releases norepinephrine, and MAO inhibition prevents catecholamine breakdown. The combination can precipitate hypertensive crisis with severe headache, arrhythmia and intracranial hemorrhage.
Ce que signifie cette interaction, en termes simples
Benzphetamine and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Increased release of norepinephrine combined with blocked MAO-mediated catecholamine degradation causes exaggerated pressor responses.
Conduite à tenir
Do not use during or within 14 days of stopping tranylcypromine. Choose a non-sympathomimetic weight management approach.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Tranylcypromine
- 5-HTP + Tranylcypromine Contre-indiquée
- Amitriptyline + Tranylcypromine Contre-indiquée
- Amoxapine + Tranylcypromine Contre-indiquée
- Atomoxetine + Tranylcypromine Contre-indiquée
- Brimonidine + Tranylcypromine Contre-indiquée
- Buprenorphine long-acting + Tranylcypromine Contre-indiquée
Questions fréquentes
Can I take Benzphetamine with Tranylcypromine?
MediHelp rates the interaction as contraindicated. Benzphetamine and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Benzphetamine is a sympathomimetic anorectic that releases norepinephrine, and MAO inhibition prevents catecholamine breakdown. The combination can precipitate hypertensive crisis with severe headache, arrhythmia and intracranial hemorrhage.
How serious is the interaction between Benzphetamine and Tranylcypromine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use during or within 14 days of stopping tranylcypromine. Choose a non-sympathomimetic weight management approach.
What other medicines interact with Tranylcypromine?
MediHelp also lists interactions of Tranylcypromine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Tranylcypromine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
