Interactions médicamenteuses
Bictegravir + Magnesium hydroxide
Gravité: Modérée
Bictegravir and Magnesium hydroxide: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Magnesium-containing antacids bind bictegravir in the gut and lower its absorption, which may reduce antiviral efficacy and risk virologic failure or resistance. The effect depends on the timing of the doses.
Ce que signifie cette interaction, en termes simples
Bictegravir and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Divalent magnesium cations chelate the integrase inhibitor in the GI tract, reducing absorption.
Conduite à tenir
Take bictegravir at least 2 hours before magnesium antacids under fasting conditions. Avoid taking them together or taking the antacid within 2 hours before bictegravir.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Bictegravir et Magnesium hydroxide, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.
Autres interactions de Magnesium hydroxide
Questions fréquentes
Can I take Bictegravir with Magnesium hydroxide?
MediHelp rates the interaction as moderate. Bictegravir and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing antacids bind bictegravir in the gut and lower its absorption, which may reduce antiviral efficacy and risk virologic failure or resistance. The effect depends on the timing of the doses.
How serious is the interaction between Bictegravir and Magnesium hydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take bictegravir at least 2 hours before magnesium antacids under fasting conditions. Avoid taking them together or taking the antacid within 2 hours before bictegravir.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
