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Interactions médicamenteuses

Gemifloxacin + Magnesium hydroxide

Gravité: Majeure

Gemifloxacin and Magnesium hydroxide: major interaction.

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Résumé

Magnesium-containing antacids chelate gemifloxacin and reduce its absorption, risking subtherapeutic antibiotic levels.

Ce que signifie cette interaction, en termes simples

Gemifloxacin and Magnesium hydroxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Gemifloxacin belongs to Anti Bacterial; Magnesium hydroxide belongs to Gastrointestinal Tract.

Niveau de preuve: High

Pourquoi elle survient

Chelation of gemifloxacin by magnesium cations in the gut reduces absorption.

Conduite à tenir

Give gemifloxacin at least 2 hours before or 3 hours after magnesium hydroxide.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Gemifloxacin with Magnesium hydroxide?

MediHelp rates the interaction as major. Gemifloxacin and Magnesium hydroxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium-containing antacids chelate gemifloxacin and reduce its absorption, risking subtherapeutic antibiotic levels.

How serious is the interaction between Gemifloxacin and Magnesium hydroxide?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give gemifloxacin at least 2 hours before or 3 hours after magnesium hydroxide.

What other medicines interact with Magnesium hydroxide?

MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Levofloxacin. The full list is on the Magnesium hydroxide page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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