Interactions médicamenteuses
Magnesium hydroxide + Ofloxacin
Gravité: Majeure
Magnesium hydroxide and Ofloxacin: major interaction.
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Résumé
Magnesium hydroxide chelates ofloxacin in the gut and reduces its absorption, which may result in subtherapeutic levels.
Ce que signifie cette interaction, en termes simples
Magnesium hydroxide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Magnesium hydroxide belongs to Gastrointestinal Tract; Ofloxacin belongs to Anti Bacterial.
Pourquoi elle survient
Chelation of ofloxacin by magnesium cations in the gastrointestinal tract reduces absorption.
Conduite à tenir
Give ofloxacin at least 2 hours before or after magnesium hydroxide.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Magnesium hydroxide
Autres interactions de Ofloxacin
- Ofloxacin + Thioridazine Contre-indiquée
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- Amiodarone + Ofloxacin Majeure
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- Anagrelide + Ofloxacin Majeure
- Arsenic trioxide + Ofloxacin Majeure
Questions fréquentes
Can I take Magnesium hydroxide with Ofloxacin?
MediHelp rates the interaction as major. Magnesium hydroxide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium hydroxide chelates ofloxacin in the gut and reduces its absorption, which may result in subtherapeutic levels.
How serious is the interaction between Magnesium hydroxide and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ofloxacin at least 2 hours before or after magnesium hydroxide.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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