Interactions médicamenteuses
Cangrelor + Warfarin
Gravité: Modérée
Cangrelor and Warfarin: moderate interaction.
Dernière mise à jour
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Résumé
Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.
Ce que signifie cette interaction, en termes simples
Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cangrelor belongs to Cardiovascular; Warfarin belongs to Cardiovascular.
Pourquoi elle survient
Additive pharmacodynamic effect of P2Y12 platelet inhibition and vitamin K antagonist anticoagulation.
Conduite à tenir
Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Warfarin
- Defibrotide + Warfarin Contre-indiquée
- Ketorolac + Warfarin Contre-indiquée
- Abciximab + Warfarin Majeure
- Acetylsalicylic acid + Warfarin Majeure
- Adagrasib + Warfarin Majeure
- Amiodarone + Warfarin Majeure
Autres interactions de Cangrelor
- Cangrelor + Clopidogrel Majeure
- Cangrelor + Prasugrel Majeure
Questions fréquentes
Can I take Cangrelor with Warfarin?
MediHelp rates the interaction as moderate. Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.
How serious is the interaction between Cangrelor and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
