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Interactions médicamenteuses

Carbamazepine + Finerenone

Gravité: Contre-indiquée

Carbamazepine and Finerenone: contraindicated interaction.

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Résumé

Carbamazepine, a strong CYP3A4 inducer, markedly reduces finerenone exposure and its renal and cardiovascular benefit.

Ce que signifie cette interaction, en termes simples

Carbamazepine and Finerenone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Carbamazepine belongs to Central Nervous System; Finerenone belongs to Cardiovascular.

Niveau de preuve: Moderate

Pourquoi elle survient

Carbamazepine induces CYP3A4, increasing finerenone clearance.

Conduite à tenir

Avoid combination; labeling advises against strong CYP3A4 inducers. Use a non-inducing anticonvulsant if possible.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Carbamazepine with Finerenone?

MediHelp rates the interaction as contraindicated. Carbamazepine and Finerenone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Carbamazepine, a strong CYP3A4 inducer, markedly reduces finerenone exposure and its renal and cardiovascular benefit.

How serious is the interaction between Carbamazepine and Finerenone?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combination; labeling advises against strong CYP3A4 inducers. Use a non-inducing anticonvulsant if possible.

What other medicines interact with Carbamazepine?

MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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