Drug interactions
Carbamazepine + Finerenone
Severity: Contraindicated
Carbamazepine and Finerenone: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbamazepine, a strong CYP3A4 inducer, markedly reduces finerenone exposure and its renal and cardiovascular benefit.
What this interaction means in plain words
Carbamazepine and Finerenone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Carbamazepine belongs to Central Nervous System; Finerenone belongs to Cardiovascular.
Why it happens
Carbamazepine induces CYP3A4, increasing finerenone clearance.
What to do
Avoid combination; labeling advises against strong CYP3A4 inducers. Use a non-inducing anticonvulsant if possible.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Carbamazepine
- Artemether / lumefantrine + Carbamazepine Contraindicated
- Cabotegravir + Carbamazepine Contraindicated
- Carbamazepine + Delamanid Contraindicated
- Carbamazepine + Dienogest / estradiol valerate Contraindicated
- Carbamazepine + Doravirine Contraindicated
- Carbamazepine + Elbasvir / grazoprevir Contraindicated
Other interactions of Finerenone
- Clarithromycin + Finerenone Contraindicated
- Ensitrelvir + Finerenone Contraindicated
- Finerenone + Itraconazole Contraindicated
- Finerenone + Ketoconazole Contraindicated
- Finerenone + Posaconazole Contraindicated
- Finerenone + Ritonavir Contraindicated
Frequently asked questions
Can I take Carbamazepine with Finerenone?
MediHelp rates the interaction as contraindicated. Carbamazepine and Finerenone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Carbamazepine, a strong CYP3A4 inducer, markedly reduces finerenone exposure and its renal and cardiovascular benefit.
How serious is the interaction between Carbamazepine and Finerenone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combination; labeling advises against strong CYP3A4 inducers. Use a non-inducing anticonvulsant if possible.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
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