Interactions médicamenteuses
Carbonyl iron + Trientine
Gravité: Modérée
Carbonyl iron and Trientine: moderate interaction.
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Résumé
Oral iron and trientine chelate each other in the gut, reducing absorption of both and possibly weakening copper removal in Wilson disease. Iron-trientine complexes may also irritate the gut.
Ce que signifie cette interaction, en termes simples
Carbonyl iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Trientine belongs to Miscellaneous.
Pourquoi elle survient
Trientine chelates iron in the gastrointestinal tract, forming poorly absorbed complexes.
Conduite à tenir
Give iron at least 2 hours apart from trientine. Monitor copper and iron indices.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Carbonyl iron
Autres interactions de Trientine
- Calcium + Trientine Modérée
- Copper + Trientine Modérée
- Ferrous fumarate + Trientine Modérée
- Ferrous gluconate + Trientine Modérée
- Ferrous sulfate + Trientine Modérée
- Iron + Trientine Modérée
Questions fréquentes
Can I take Carbonyl iron with Trientine?
MediHelp rates the interaction as moderate. Carbonyl iron and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron and trientine chelate each other in the gut, reducing absorption of both and possibly weakening copper removal in Wilson disease. Iron-trientine complexes may also irritate the gut.
How serious is the interaction between Carbonyl iron and Trientine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give iron at least 2 hours apart from trientine. Monitor copper and iron indices.
What other medicines interact with Carbonyl iron?
MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.
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