Interactions médicamenteuses
Caspofungin + Cyclosporine
Gravité: Modérée
Caspofungin and Cyclosporine: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Cyclosporine increases caspofungin exposure, and transient rises in liver transaminases have been seen when the two are given together. Caspofungin does not meaningfully change cyclosporine levels.
Ce que signifie cette interaction, en termes simples
Caspofungin and Cyclosporine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Cyclosporine inhibits OATP-mediated hepatic uptake of caspofungin, raising its plasma concentrations.
Conduite à tenir
Monitor liver enzymes during coadministration and consider stopping if significant hepatic abnormalities develop.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Caspofungin et Cyclosporine, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.
Autres interactions de Caspofungin
- Apalutamide + Caspofungin Modérée
- Carbamazepine + Caspofungin Modérée
- Caspofungin + Cyclosporin Modérée
- Caspofungin + Dexamethasone Modérée
- Caspofungin + Efavirenz Modérée
- Caspofungin + Fosphenytoin Modérée
Questions fréquentes
Can I take Caspofungin with Cyclosporine?
MediHelp rates the interaction as moderate. Caspofungin and Cyclosporine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine increases caspofungin exposure, and transient rises in liver transaminases have been seen when the two are given together. Caspofungin does not meaningfully change cyclosporine levels.
How serious is the interaction between Caspofungin and Cyclosporine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor liver enzymes during coadministration and consider stopping if significant hepatic abnormalities develop.
What other medicines interact with Caspofungin?
MediHelp also lists interactions of Caspofungin with, for example, Apalutamide, Carbamazepine, Cyclosporin. The full list is on the Caspofungin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
