Aller au contenu

Interactions médicamenteuses

Caspofungin + Dexamethasone

Gravité: Modérée

Caspofungin and Dexamethasone: moderate interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Dexamethasone may reduce caspofungin concentrations and could weaken antifungal efficacy. Caspofungin labeling lists dexamethasone among inducers for which a higher dose may be considered.

Ce que signifie cette interaction, en termes simples

Caspofungin and Dexamethasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Caspofungin belongs to Anti Fungals; Dexamethasone belongs to Endocrine.

Niveau de preuve: Moderate

Pourquoi elle survient

Proposed induction of caspofungin clearance (via hepatic uptake or metabolism pathways) by dexamethasone; the exact mechanism is not firmly established.

Conduite à tenir

Consider a caspofungin maintenance dose of 70 mg daily in adults if the response is inadequate, and monitor clinical response.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Caspofungin et Dexamethasone, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.

Questions fréquentes

Can I take Caspofungin with Dexamethasone?

MediHelp rates the interaction as moderate. Caspofungin and Dexamethasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexamethasone may reduce caspofungin concentrations and could weaken antifungal efficacy. Caspofungin labeling lists dexamethasone among inducers for which a higher dose may be considered.

How serious is the interaction between Caspofungin and Dexamethasone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider a caspofungin maintenance dose of 70 mg daily in adults if the response is inadequate, and monitor clinical response.

What other medicines interact with Caspofungin?

MediHelp also lists interactions of Caspofungin with, for example, Apalutamide, Carbamazepine, Cyclosporin. The full list is on the Caspofungin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter