Interactions médicamenteuses
Cefaclor + Cholera vaccine
Gravité: Modérée
Cefaclor and Cholera vaccine: moderate interaction.
Dernière mise à jour
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Résumé
The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response. Cefaclor activity against Vibrio cholerae is uncertain, but labeling advises caution with antibiotics in general.
Ce que signifie cette interaction, en termes simples
Cefaclor and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Antibacterial activity may inhibit replication of the live attenuated vaccine strain, lowering immunogenicity.
Conduite à tenir
Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefaclor
- Bcg vaccine live + Cefaclor Modérée
- Cefaclor + Kanamycin Modérée
- Cefaclor + Microbiota Modérée
- Cefaclor + Plazomicin Modérée
- Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid Modérée
- Cefaclor + Typhoid vaccine live Modérée
Questions fréquentes
Can I take Cefaclor with Cholera vaccine?
MediHelp rates the interaction as moderate. Cefaclor and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response. Cefaclor activity against Vibrio cholerae is uncertain, but labeling advises caution with antibiotics in general.
How serious is the interaction between Cefaclor and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Kanamycin, Microbiota. The full list is on the Cefaclor page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
