Interactions médicamenteuses
Cefaclor + Plazomicin
Gravité: Modérée
Cefaclor and Plazomicin: moderate interaction.
Dernière mise à jour
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Résumé
Plazomicin carries warnings for nephrotoxicity, ototoxicity and neuromuscular blockade. Cephalosporins have occasionally been associated with additive kidney injury when combined with aminoglycosides, although cefaclor has relatively low nephrotoxic potential.
Ce que signifie cette interaction, en termes simples
Cefaclor and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefaclor belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Pourquoi elle survient
Additive nephrotoxic effects on the renal tubule.
Conduite à tenir
Monitor serum creatinine and plazomicin concentrations during combined use, and adjust the plazomicin dose to renal function per labeling.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefaclor
Autres interactions de Plazomicin
- Cefadroxil + Plazomicin Modérée
- Cefalexin + Plazomicin Modérée
- Cefazolin + Plazomicin Modérée
- Cefditoren + Plazomicin Modérée
- Cefepime + Plazomicin Modérée
- Cefixime + Plazomicin Modérée
Questions fréquentes
Can I take Cefaclor with Plazomicin?
MediHelp rates the interaction as moderate. Cefaclor and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin carries warnings for nephrotoxicity, ototoxicity and neuromuscular blockade. Cephalosporins have occasionally been associated with additive kidney injury when combined with aminoglycosides, although cefaclor has relatively low nephrotoxic potential.
How serious is the interaction between Cefaclor and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations during combined use, and adjust the plazomicin dose to renal function per labeling.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
