Interactions médicamenteuses
Cefepime + Microbiota
Gravité: Modérée
Cefepime and Microbiota: moderate interaction.
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Résumé
Oral microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is partly excreted into the gut lumen may reduce the viability of the spores and blunt the preventive effect against recurrent Clostridioides difficile infection.
Ce que signifie cette interaction, en termes simples
Cefepime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
The antibacterial activity of the cephalosporin can reduce the viability of the live bacterial spores in the product.
Conduite à tenir
Finish the antibiotic course before starting oral microbiota therapy, and keep the labeled interval after the last antibiotic dose (typically 2 to 4 days).
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefepime
- Amikacin + Cefepime Modérée
- Cefepime + Cholera vaccine Modérée
- Cefepime + Dexamethasone-tobramycin Modérée
- Cefepime + Gentamicin Modérée
- Cefepime + Kanamycin Modérée
- Cefepime + Plazomicin Modérée
Questions fréquentes
Can I take Cefepime with Microbiota?
MediHelp rates the interaction as moderate. Cefepime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is partly excreted into the gut lumen may reduce the viability of the spores and blunt the preventive effect against recurrent Clostridioides difficile infection.
How serious is the interaction between Cefepime and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course before starting oral microbiota therapy, and keep the labeled interval after the last antibiotic dose (typically 2 to 4 days).
What other medicines interact with Cefepime?
MediHelp also lists interactions of Cefepime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Cefepime page.
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