Interactions médicamenteuses
Chlorthalidone + Miglitol
Gravité: Modérée
Chlorthalidone and Miglitol: moderate interaction.
Dernière mise à jour
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Résumé
Chlorthalidone can raise blood glucose and so reduce the effect of miglitol. The effect is usually modest but may worsen postprandial control.
Ce que signifie cette interaction, en termes simples
Chlorthalidone and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorthalidone belongs to Cardiovascular; Miglitol belongs to Endocrine.
Pourquoi elle survient
Thiazide-induced hypokalemia and reduced insulin secretion and sensitivity oppose the antihyperglycemic effect.
Conduite à tenir
Monitor blood glucose and HbA1c after starting or changing chlorthalidone and adjust therapy as needed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Chlorthalidone
Autres interactions de Miglitol
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- Aripiprazole + Miglitol Modérée
- Asenapine + Miglitol Modérée
- Clozapine + Miglitol Modérée
- Cortisone + Miglitol Modérée
- Darunavir + Miglitol Modérée
Questions fréquentes
Can I take Chlorthalidone with Miglitol?
MediHelp rates the interaction as moderate. Chlorthalidone and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlorthalidone can raise blood glucose and so reduce the effect of miglitol. The effect is usually modest but may worsen postprandial control.
How serious is the interaction between Chlorthalidone and Miglitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c after starting or changing chlorthalidone and adjust therapy as needed.
What other medicines interact with Chlorthalidone?
MediHelp also lists interactions of Chlorthalidone with, for example, Amifostine, Atenolol-chlorthalidone, Candesartan-hydrochlorothiazide. The full list is on the Chlorthalidone page.
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